Evidence-based anti-viral and immunomodulatory potential of Black cumin (Nigella sativaL.) in COVID-19

Currently, the whole world is facing a life-threatening novel coronavirus 2019 (COVID-19) pandemic. Natural products are well-known for their potential role against viral disease, and some anti-viral agents have been developed to combat these diseases. Herein, authors investigated possible effects of this Holy plant Nigella sativaL. (NS), coronavirus, using evidence-based mechanistic approaches conclude immune-boosting alleviation respiratory systemeffects NS. The pharmacological studies established prominent in treating various respiratory, immune systems, cardiovascular, skin, gastrointestinal disorders. Literature supported significant showed an inhibitory NS MHV-A59 CoV (mouse-hepatitis virus–A59) infected Hela, i.e., HeLaCEACAM1a (HeLa-epithelial carcinoembryonic antigen-related cell adhesion molecule 1a) cell. safe herbal product or dietary supplement could be effective affordable community adjuvant treatment current scenario.